CD45/LCA (Leucocyte Marker)
CAT:
544-MBS4380669-03
Size:
0.1 mg (Without BSA & Azide at 1mg/mL)
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD45/LCA (Leucocyte Marker)
- Gene Name: [CD45/LCA]
- NCBI Gene ID: 5788
- Reactivity: Human. Others not known.
- Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required. - Specificity: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
- Other Gene Names: [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; L-CA]
- Short Name: [CD45/LCA]
- Other Product Names: [receptor-type tyrosine-protein phosphatase C isoform 1; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; protein tyrosine phosphatase, receptor type C; Leukocyte common antigen; L-CA; T200; CD_antigen: CD45]
- NCBI GI Number: 392307007
- NCBI Accession Number: NP_002829.3
- NCBI GB Accession Number: NM_002838.4
- Uniprot Accession Number: P08575