Smooth Muscle Myosin Heavy Chain (SM-MHC)

• Gene Name:

  [SM-MHC]

• NCBI Gene ID:

  4629

• Reactivity:

  Human, Cow, Pig, Dog, Cat, Rabbit, Rat, Guinea pig, Chicken. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

• Other Gene Names:

  [MYH11; MYH11; AAT4; FAA4; SMHC; SMMHC; KIAA0866]

• Short Name:

  [Smooth Muscle Myosin Heavy Chain (SM-MHC)]

• Other Product Names:

  [myosin-11 isoform SM2B; Myosin-11; myosin-11; myosin heavy chain 11; Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC]

• NCBI GI Number:

  92091583

• NCBI Accession Number:

  NP_001035202.1

• NCBI GB Accession Number:

  NM_001040113.1

• Uniprot Accession Number:

  P35749