IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)

IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)

• Gene Name: [IGHG]
• NCBI Gene ID: 3500
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
• Other Gene Names: [IGHG1; IGHG1]
• Short Name: [IgG (Immunoglobulin Gamma Heavy Chain)]
• Other Product Names: [Immunoglobulin heavy constant gamma 1; Immunoglobulin heavy constant gamma 1; immunoglobulin heavy constant gamma 1 (G1m marker); Ig gamma-1 chain C region]
• NCBI GI Number: 121039
• NCBI Accession Number: P01857.1
• Uniprot Accession Number: P01857