5'-Guanylic acid-15N5 (dilithium)

5'-Guanylic acid-15N5 (dilithium)

• UNSPSC Description: 5'-Guanylic acid-15N5 (5'-GMP-15N5 dilithium; 5'-guanosine monophosphate-15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/5-guanylic-acid-15n5-dilithium.html
• Purity: 95.0
• Solubility: 10 mM in DMSO
• Smiles: O=P(O[Li])(O[Li])OC[C@H]1O[C@@H]([15N]2C([15N]=C([15NH2])[15NH]C3=O)=C3[15N]=C2)[C@H](O)[C@@H]1O
• Molecular Weight: 380.05
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Blue Ice
• Storage Conditions: Solution, -20°C, 2 years
• Clinical Information: No Development Reported