REPS1 (phospho-Ser709) rabbit pAb

• Description:

  This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],

• Synonyms:

  RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)

• Gene ID:

  85021

• UniProt:

  Q96D71

• Cellular Locus:

  Membrane, clathrin-coated pit. Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Immunogen:

  Synthesized phosho peptide around human REPS1 (Ser709)

• Clonality:

  Polyclonal

• Validated Applications:

  WB, IHC

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000;IHC-p 1:50-300

• Molecular Weight:

  80kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.