11-Dehydro-thromboxane B2-13C5

• UNSPSC Description:

  11-Dehydro-thromboxane B2-13C5 is 13C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

• Target Antigen:

  Endogenous Metabolite; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease;Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/11-dehydro-thromboxane-b2-13c5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[13C]([13CH2][13CH2][13CH2]/[13CH]=C/C[C@H]([C@H](O1)/C=C/[C@H](CCCCC)O)[C@H](CC1=O)O)O

• Molecular Weight:

  373.43

• References & Citations:

  [1]Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78. |[2]Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5(2):115-27. |[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported