HIF-2α-IN-3
CAT:
804-HY-18370-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HIF-2α-IN-3
- CAS Number: 313964-19-1
- UNSPSC Description: HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α (HIF-2α), exhibits an IC50 of 0.4 μM and a KD of 1.1 μM. Anticancer agent[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hif-2α-in-3.html
- Purity: 99.89
- Solubility: DMSO : 12.5 mg/mL (ultrasonic)
- Smiles: O=[N+](C1=C(NC2=CC=C(Cl)C([N+]([O-])=O)=C2)C=CC3=NON=C31)[O-]
- Molecular Weight: 335.66
- References & Citations: [1]Rogers JL, et al. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. J Med Chem. 2013 Feb 28;56(4):1739-47.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported