Frizzled-4 rabbit pAb

• Description:

  Frizzled class receptor 4 (FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],

• Synonyms:

  FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

• Gene ID:

  8322

• UniProt:

  Q9ULV1

• Cellular Locus:

  Cell membrane ; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180

• Clonality:

  Polyclonal

• Validated Applications:

  IF, ELISA

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.