VPS54 rabbit pAb

• Background:

  This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008],

• Synonyms:

  VPS54; HCC8; Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p

• Gene ID:

  51542

• UniProt:

  Q9P1Q0

• Cellular Locus:

  Golgi apparatus, trans-Golgi network. Membrane. Associates with membranes in an EIPR1-independent manner..

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from the Internal region of human VPS54.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Validated Applications:

  IHC, IF, ELISA

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Golgi apparatus, trans-Golgi network . Membrane . Associates with membranes in an EIPR1-independent manner. .

• Other Product Names:

  VPS54; HCC8; Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p

• Gene ID (Human):

  51542

• SwissProt (Human):

  Q9P1Q0