Nectin 3 rabbit pAb

• Description:

  This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],

• Synonyms:

  PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD antigen CD113

• Gene ID:

  25945

• UniProt:

  Q9NQS3

• Cellular Locus:

  Cell membrane ; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human PVRL3. AA range:184-233

• Clonality:

  Polyclonal

• Validated Applications:

  WB, ELISA

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  61kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.