Metallo-β-lactamase-IN-15

Metallo-β-lactamase-IN-15

• CAS Number: 1804934-57-3
• UNSPSC Description: Metallo-β-lactamase-IN-15 (Compound ±13) is a potent MBL inhibitor, the IC50 values for NDM-1、IMP-1 and VIM-2 were 0.29 μM, 0.088 μM and 0.063 μM, respectively[1].
• Target Antigen: Beta-lactamase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/metallo-β-lactamase-in-15.html
• Solubility: 10 mM in DMSO
• Smiles: SC[C@H]1SC[C@]2([H])SC3=CC=CC=C3N21
• Molecular Weight: 241.40
• References & Citations: [1]Villamil, Valentina et al. “Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes.” Journal of medicinal chemistry, 19 Feb. 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported