CLK1/2-IN-1

• CAS Number:

  1005784-23-5

• UNSPSC Description:

  CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/clk1-2-in-1.html

• Purity:

  99.87

• Solubility:

  DMSO : ≥ 200 mg/mL

• Smiles:

  O=C(NC1=CN2C=C(C(F)(F)F)C=CC2=N1)C3=CC=C(C(C)(C)CCC4=NNN=N4)C=C3

• Molecular Weight:

  443.43

• References & Citations:

  [1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported