PRMT5-IN-25

• CAS Number:

  2691869-82-4

• UNSPSC Description:

  PRMT5-IN-25 (compound 503) is a potent PRMT5 inhibitor with an Ki value of 0.06 nM. PRMT5-IN-25 shows antiproliferative[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-25.html

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=CC=C2N=C(N)C(C)=CC2=C1)N([C@@H](C3=NC=CC=N3)C)CC4=NC=C(C(F)(F)F)C=C4

• Molecular Weight:

  466.46

• References & Citations:

  [1]Jennifer Rebecca Allen, et al. Novel prmt5 inhibitors. WO2021163344A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported