GRO-alpha/CXCL1, Human

GRO-alpha/CXCL1, Human

• UNSPSC Description: CXCL1 (Chemokine (C-X-C motif) ligand 1), also known as GRO alpha, NAP-3 or MGSA, belongs to the sub-family of CXC chemokine. CXCL1 is involved in the development of many inflammatory diseases, including the induction of angiogenesis and recruitment of neutrophils. CXCL1 is produced by many cell types, and activates CXCR2 and, at high levels, CXCR1[1]. GRO-alpha/CXCL1 Protein, Human is produced in E. coli, and consists of 73 amino acids (A35-N107).
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/gro-alpha-cxcl1-protein-human.html
• Purity: 95.0
• Smiles: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN
• Molecular Weight: Approximately 7.8 kDa
• References & Citations: [1]Dhawan P, et al. Role of CXCL1 in tumorigenesis of melanoma. J Leukoc Biol. 2002 Jul;72(1):9-18.|[2]Haskill S, et al. Identification of three related human GRO genes encoding cytokine functions. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7732-6.|[3]Moser B, et al. Neutrophil-activating properties of the melanoma growth-stimulatory activity. J Exp Med. 1990 May 1;171(5):1797-802.|[4]Vries MH, et al. CXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space. Angiogenesis. 2015 Apr;18(2):163-71.
• Shipping Conditions: Blue Ice
• Storage Conditions: Stored at -20°C for 2 years