Cefuroxime

Cefuroxime

• CAS Number: 55268-75-2
• UNSPSC Description: Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].
• Target Antigen: Antibiotic; Bacterial; Beta-lactamase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/cefuroxime.html
• Purity: 99.08
• Solubility: DMSO : 116.67 mg/mL (ultrasonic)
• Smiles: O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O
• Molecular Weight: 424.39
• References & Citations: [1]Callaghan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vitro. Antimicrob Agents Chemother. 1976 Mar;9(3):511-9.|[2]D M Ryan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9(3):520-5.Adv Funct Mater. 2024 Jun 19.|Nat Commun. 2022 Mar 2;13(1):1116.|Nat Commun. 2023 Mar 22;14(1):1594.|Biomed Res Int. 2018 Jul 2;2018:3579832. |Int J Antimicrob Agents. 2024 May 30:107229.|J Chem Inf Model. 2021 Mar 18.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched