MHY 553

CAT:

804-HY-128135

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CAS Number: 6265-56-1
UNSPSC Description: MHY 553 is an oral PPARα agonist that alleviates liver steatosis by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY553 inhibits triglyceride accumulation induced by liver X receptor agonists in HepG2 cells. MHY553 significantly suppresses inflammatory mRNA expression in aged rats[1].
Target Antigen: PPAR
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/mhy-553.html
Smiles: OC1=CC=C(C2=NC3=CC=CC=C3S2)C(O)=C1
Molecular Weight: 243.28
References & Citations: [1]Seong Min Kim, et al. Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget. 2017 May 8;8(28):46273–46285.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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