Dovitinib-RIBOTAC

• CAS Number:

  2759351-68-1

• UNSPSC Description:

  Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

• Target Antigen:

  PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dovitinib-ribotac.html

• Solubility:

  DMSO : 130 mg/mL (ultrasonic)

• Smiles:

  O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1

• Molecular Weight:

  1006.11

• References & Citations:

  [1]Zhang P, et al. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported