IHMT-MST1-58

• CAS Number:

  2414484-25-4

• UNSPSC Description:

  IHMT-MST1-58 is a potent, selective mammalian and orally active STE20-like protein 1 kinase (MST1) inhibitor with IC50 value of 23 nM. IHMT-MST1-58 can be used for the research of Type 1/2 diabetes[1].

• Target Antigen:

  Hippo (MST)

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ihmt-mst1-58.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  O=S(C1=CC=C(NC(N=C2N(C)C3C4=CC=CC=C4C)=NC=C2N(C)C3=O)C=C1)(N)=O

• Molecular Weight:

  438.50

• References & Citations:

  [1]Yun Wu, et al. Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes. J Med Chem. 2022 Sep 8;65(17):11818-11839

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported