GSK 2830371
CAT:
804-HY-15832-06
Size:
200 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

GSK 2830371
- CAS Number: 1404456-53-6
- UNSPSC Description: GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM.
- Target Antigen: Phosphatase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/gsk-2830371.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: ClC1=CN=C(C)C(NCC2=CC=C(C(N[C@@H](CC3CCCC3)C(NC4CC4)=O)=O)S2)=C1
- Molecular Weight: 461.02
- References & Citations: [1]Gilmartin AG, et al. Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction. Nat Chem Biol. 2014 Mar;10(3):181-7.|[2]Esfandiari A, et al. Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. Mol Cancer Ther. 2016 Mar;15(3):379-91.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported