HAT1 (KAT1), FLAG-Tag Recombinant

• Background:

  HAT1 (histone acetyltransferase 1), also known as KAT1, regulates chromatin structure, mitochondrial function, and DNA repair. HAT1 acetylates newly synthesized histones in the cytoplasm and succinylates histones and non-histone proteins. The epigenetic regulation activity of this protein is involved in a wide variety of diseases such as cancer, inflammatory diseases, and viral infections. The development of inhibitors targeting HAT1 may open new therapeutic avenues in those disorders.

• Description:

  Recombinant human full-length HAT1 (histone acetyltransferase 1), also known as KAT1, amino acids 2-419 (end) . This construct contains an N-terminal FLAG-tag. The recombinant protein was affinity purified.

• UniProt:

  O14929

• Tag:

  N-terminal FLAG-tag

• Applications:

  Useful for SDS-PAGE.

• Purity:

  ≥ 90%

• Format:

  Aqueous buffer solution

• Shipping Conditions:

  -80°C

• Storage Conditions:

  At least 6 months at -80°C.

• Calculated Molecular Weight:

  51 kDa

• Formulation:

  40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 80 ng/µl FLAG peptide, and 20% glycerol.