Human Recombinant FcγRIIb/CD32B

• Short Description:

  Catalog Number: B2017031 (50 µg)_x000D_ Human Recombinant FcγRIIb/CD32B is a high quality receptor protein found on the surface of certain immune cells, such as B cells and macrophages. It is involved in regulating immune responses by binding to antibodies, particularly immunoglobulin G (IgG). This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Description:

  Human Recombinant FcγRIIb/CD32B _x000D_ Catalog number: B2017031_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 20.8 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: CDw32, Fc-γ RII-b, FcγRIIB, FcRII-b, IgG Fc Receptor II-b, Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Veri MC, Gorlatov S, Li H, Burke S, Johnson S, Stavenhagen J, Stein KE, Bonvini E, Koenig S. Monoclonal antibodies capable of discriminating the human inhibitory Fcgamma-receptor IIB (CD32B) from the activating Fcgamma-receptor IIA (CD32A): biochemical, biological and functional characterization Immunology. 2007 Jul;121(3):392-404._x000D_ 2: Crawford JR, Pilling D, Gomer RH. FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation J Leukoc Biol. 2012 Oct;92(4):699-711._x000D_ 3: Moraru M, Perez-Portilla A, Al-Akioui Sanz K, Blazquez-Moreno A, Arnaiz-Villena A, Reyburn HT, Vilches C. FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene Front Immunol. 2021 May 24;12:615645._x000D_ 4: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes J Leukoc Biol. 2008 Oct;84(4):1109-19._x000D_ 5: Hör S, Ziv T, Admon A, Lehner PJ. Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase Mol Cell Proteomics. 2009 Aug;8(8):1959-71._x000D_ 6: Xu Z, Liu L, Cui Z, Bi K, Zhang N, Zhang Y, Liu Z. The Unique Inhibitory IgG Receptor--FcγRIIb Protein Pept Lett. 2018;25(11):966-972._x000D_ 7: Zhang K, Zhu D, Kepley C, Terada T, Saxon A. Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy Immunol Allergy Clin North Am. 2007 Feb;27(1):93-103._x000D_ 8: Saxon A, Kepley C, Zhang K. "Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling J Allergy Clin Immunol. 2008 Feb;121(2):320-5._x000D_ 9: Magnusson SE, Andrén M, Nilsson KE, Sondermann P, Jacob U, Kleinau S. Amelioration of collagen-induced arthritis by human recombinant soluble FcgammaRIIb Clin Immunol. 2008 May;127(2):225-33._x000D_ 10: Jiang VC, Liu Y, Jordan A, Leeming A, McIntosh J, Huang S, Zhang R, Cai Q, Chen Z, Li Y, Che Y, Nie L, Karlsson I, MÃ¥rtensson L, Kovacek M, Teige I, Frendéus B, Wang M. Targeting FcγRIIB by antagonistic antibody BI-1206 improves the efficacy of rituximab-based therapies in aggressive mantle cell lymphoma J Hematol Oncol. 2022 Apr 11;15(1):42. _x000D_ _x000D_ Products Related to Human Recombinant FcγRIIb/CD32B can be found at Proteins

• CAS Number:

  9000-83-3

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5