ATUX-1215

• CAS Number:

  2910929-53-0

• UNSPSC Description:

  ATUX-1215 is an activator of protein phosphatase 2A (PP2A). ATUX-1215 reduced the phosphorylation of ERK, p38, JNK, and Akt and the secretion of IL-12p70, GM-CSF, and IL1α in BLM-treated animals. ATUX-1215 can slow the progression of lung fibrosis[1].

• Target Antigen:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/atux-1215.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=S(NC1CC(OCC1)C2C3=CC=C(F)C=C3CCC4=CC(F)=CC=C42)(C5=CC=C(C=C5)OC(F)(F)F)=O

• Molecular Weight:

  553.54

• References & Citations:

  [1]Meshach Pillai, et al. Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice. 2023.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported