NSE gamma (Neuron Specific Enolase, gamma) (Neuroendocrine Marker)

• Gene Name:

  [NSE gamma]

• NCBI Gene ID:

  2026

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.

• Other Gene Names:

  [ENO2; ENO2; NSE; HEL-S-279; NSE]

• Short Name:

  [NSE gamma (Neuron Specific Enolase, gamma)]

• Other Product Names:

  [gamma-enolase; Gamma-enolase; gamma-enolase; enolase 2; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE]

• NCBI GI Number:

  5803011

• NCBI Accession Number:

  NP_001966.1

• NCBI GB Accession Number:

  NM_001975.2

• Uniprot Accession Number:

  P09104