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Catenin, beta (p120)

CAT:
544-MBS439899-04
Size:
5x 0.1 mg (With BSA & Azide at 0.2mg/mL)
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Catenin, beta (p120) - image 1

Catenin, beta (p120)

  • Gene Name: [CTNNB1]
  • NCBI Gene ID: 1499
  • Reactivity: Human, Cow, Dog, Chicken. Others not known.
  • Storage Conditions: Antibody with azide - store at 2 to 8 °C.
    Antibody without azide - store at -20 to -80 °C.
    Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • Specificity: This MAb recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
  • Other Gene Names: [CTNNB1; CTNNB1; EVR7; CTNNB; MRD19; armadillo; CTNNB]
  • Short Name: [Catenin, beta]
  • Other Product Names: [catenin beta-1 isoform 1; Catenin beta-1; catenin beta-1; catenin beta 1; Beta-catenin]
  • NCBI GI Number: 148233338
  • NCBI Accession Number: NP_001091679.1
  • NCBI GB Accession Number: NM_001098209.1
  • Uniprot Accession Number: P35222