CDX2 (GI Epithelial Marker)

• Gene Name: [CDX2]
• NCBI Gene ID: 1045
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
• Other Gene Names: [CDX2; CDX2; CDX3; CDX-3; CDX2/AS; CDX3]
• Short Name: [CDX2]
• Other Product Names: [homeobox protein CDX-2 isoform 1; Homeobox protein CDX-2; homeobox protein CDX-2; caudal type homeobox 2; CDX-3; Caudal-type homeobox protein 2]
• NCBI GI Number: 372624392
• NCBI Accession Number: NP_001256.3
• NCBI GB Accession Number: NM_001265.5
• Uniprot Accession Number: Q99626