CD100 (Semaphorin-4D) Mouse Monoclonal Antibody

• CAS Number:

  9007-83-4

• Gene Name:

  [SEMA4D]

• NCBI Gene ID:

  10507

• Reactivity:

  Human, Baboon.
  Does not react with Horse.
  Others not tested

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

• Other Gene Names:

  [SEMA4D; SEMA4D; CD100; SEMAJ; coll-4; C9orf164; M-sema-G; C9orf164; CD100; SEMAJ]

• Short Name:

  [CD100]

• Other Product Names:

  [semaphorin-4D isoform 2; Semaphorin-4D; semaphorin-4D; semaphorin 4D; A8; BB18; GR3; CD_antigen: CD100]

• NCBI GI Number:

  214010220

• NCBI Accession Number:

  NP_001135759.1

• NCBI GB Accession Number:

  NM_001142287.1

• Uniprot Accession Number:

  Q92854