CD3e (T-Cell Marker)

• Gene Name: [CD3E]
• NCBI Gene ID: 916
• Reactivity: Human
• Storage Conditions: Antibody with azide - store at 2 to 8°C. Non-hazardous. No MSDS required.
• Specificity: Recognizes the chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
• Other Gene Names: [CD3E; CD3E; T3E; TCRE; IMD18; T3E]
• Short Name: [CD3e]
• Other Product Names: [T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; CD3e molecule, epsilon (CD3-TCR complex); T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]
• NCBI GI Number: 4502671
• NCBI Accession Number: NP_000724.1
• NCBI GB Accession Number: NM_000733.3
• Uniprot Accession Number: P07766