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MOUSE ANTI HUMAN CD58:FITC

CAT:
544-MBS210848-01
Size:
100 Tests
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
MOUSE ANTI HUMAN CD58:FITC - image 1

MOUSE ANTI HUMAN CD58:FITC

  • CAS Number: 9007-83-4
  • Gene Name: [CD58]
  • NCBI Gene ID: 965
  • Storage Conditions: Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: 18 months from date of despatch.
  • Specificity: CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes[1]. It is a member of the immunoglobulin superfamily of molecules.CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells[2]. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria.
  • Other Gene Names: [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3]
  • Short Name: [CD58]
  • Other Product Names: [lymphocyte function-associated antigen 3 isoform 2; Lymphocyte function-associated antigen 3; lymphocyte function-associated antigen 3; CD58 antigen, (lymphocyte function-associated antigen 3); surface glycoprotein LFA-3; CD58 molecule; Surface glycoprotein LFA-3; CD_antigen: CD58]
  • NCBI GI Number: 221316575
  • NCBI Accession Number: NP_001138294.1
  • NCBI GB Accession Number: NM_001144822.1