Recombinant Mouse Eotaxin/CCL11 protein

• Background:

  Mouse CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Mouse CCL11 is approximately 63 % identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60 % amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor.

• CAS Number:

  9000-83-3

• Reconstitution:

  Lyophilized from a .2 μm filtered solution of 2mM Tris, 15mM NaCl, pH 8..

• Molecular Weight:

  Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.