Recombinant Mouse IL-13 protein

• Background:

  Mouse Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 11 and secreted by many cell types, especially T helper type 2 (Th2) cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 has been implicated as a key factor in asthma, allergy, atopy and inflammatory response, establishing the protein as a valuable therapeutic target. Human, mouse and rat IL-3 share low homology, but have cross species activity.

• CAS Number:

  9000-83-3

• Reconstitution:

  Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.

• Molecular Weight:

  Approximately 12.3 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.