Recombinant Mouse MCP-2/CCL8 protein

• Background:

  Mouse CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family and is encoded by the gene CCL8 in mouse. MCP-2 has two homogeneous MCP-1 (CCL2) and MCP-3 (CCL7). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL8 shares 62 % amino acid sequence identity with MCP-1, and shares 58 % amino acid sequence identity with MCP-2. CCL8 has chemotactic fuction for monocytes, eosinophils and neutrophils. In addition, it can also chemoattract activated NK cells.

• CAS Number:

  9000-83-3

• Reconstitution:

  Lyophilized from a .2 μm filtered solution in 2 mM Tris, 5 mM NaCl, pH 7.4.

• Molecular Weight:

  Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.