RUNX3 Polyclonal Antibody

• Background:

  This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

• Synonyms:

  RUNX3,AML2,CBFA3,PEBP2aC

• CAS Number:

  9007-83-4

• Gene ID:

  864

• Swiss Prot:

  Q13761

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human RUNX3 (NP_001026850.1).

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  WB,IF

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  44 kDa/45 kDa

• Observed Molecular Weight:

  44 kDa