MSTN Polyclonal Antibody

• Background:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

• Synonyms:

  MSTN,GDF8,MSLHP,myostatin

• CAS Number:

  9007-83-4

• Gene ID:

  2660

• Swiss Prot:

  O14793

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  Recombinant fusion protein of human MSTN (NP_005250.1).

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.