S100A8 Polyclonal Antibody

S100A8 Polyclonal Antibody

• Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: S100A8,60B8AG,CAGA,CFAG,CGLA,CP-10,L1Ag,MA387,MIF,MRP8,NIF,P8
• CAS Number: 9007-83-4
• Gene ID: 6279
• Swiss Prot: P05109
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: Recombinant fusion protein of human S100A8 (NP_002955.2).
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: IHC,IF
• Purification: Affinity purification
• Concentration: 1 mg/mL
• Dilution: IHC 1:50-1:100 IF 1:50-1:100
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.