Purified Anti-Human CD20 Antibody

Purified Anti-Human CD20 Antibody

• Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
• Synonyms: Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1
• CAS Number: 9007-83-4
• Gene ID: 931
• Swiss Prot: P11836
• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b κ
• Conjugation: Unconjugated
• Applications: FCM
• Concentration: 0.5 mg/mL
• Buffer: PBS with 0.05% Proclin300
• Storage Conditions: Store at 2~8°C. Do not freeze.