AF647 Anti-Human CD20 Antibody

AF647 Anti-Human CD20 Antibody

• Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
• Synonyms: B-lymphocyte antigen CD20,MS4A1,B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1,MS4A1,CD20
• CAS Number: 9007-83-4
• Gene ID: 931
• Swiss Prot: P11836
• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Conjugation: AF647
• Applications: FCM
• Buffer: PBS with 0.05% Proclin300, 1% BSA
• Storage Conditions: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.