Anti-PLCB1 Antibody Picoband®, Biotin Conjugate

Anti-PLCB1 Antibody Picoband®, Biotin Conjugate

• Background: PLCB1 is also known as PLC-I, EIEE12 or PLC154. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
• Description: Boster Bio Anti-PLCB1 Antibody Picoband® catalog # A02817-1. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
• Gene Name: PLCB1
• Gene ID: 23236
• UniProt: Q9NQ66
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: E.coli-derived human PLCB1 recombinant protein (Position: H9-D834). Human PLCB1 shares 98.8% and 98.5% amino acid (aa) sequence identity with mouse and rat PLCB1, respectively.
• Clonality: Polyclonal
• Applications: WB,ELISA
• Purification: Immunogen affinity purified.
• Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Form: Lyophilized
• Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Components: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
• References & Citations: 1. Guo Y, et al. A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress. Biochemistry, 2013 Jun 4. 2. Ngoh A, et al. Severe infantile epileptic encephalopathy due to mutations in PLCB1: expansion of the genotypic and phenotypic disease spectrum. Dev Med Child Neurol, 2014 Nov. 3. Philip F, et al. Role of phospholipase C-β in RNA interference. Adv Biol Regul, 2013 Sep.
• Storage Conditions: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
• Observed Molecular Weight: 150 kDa
• Applications Notes: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
  ELISA, 0.1-0.5 μg/ml, -