Anti-Perforin Purified PRF1 Monoclonal Antibody

Anti-Perforin Purified PRF1 Monoclonal Antibody

• Background: Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
• Description: Boster Bio Anti-Perforin Purified PRF1 Monoclonal Antibody (Catalog# M01429-1). Tested in Flow Cytometry, IP, IHC-P, IHC-F, ICC application(s). This antibody reacts with Human, Cow.
• Synonyms: PRF1, P1, PFP, HPLH2
• CAS Number: 9007-83-4
• Gene Name: PRF1
• UniProt: P14222
• Host: Mouse
• Reactivity: Human, Cow
• Immunogen: purified granules from human YT lymphoma cell line. The mouse monoclonal antibody dG9 (also known as deltaG9) recognizes perforin, a 70 kDa protein expressed in cytoplasmic granules of cytotoxic T cells and NK cells.
• Clonality: Monoclonal
• Applications: Flow Cytometry, IP, IHC-P, IHC-F, ICC
• Purification: Purified by protein-A affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 61377 MW
• Components: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Mouse IgG2b kappa
• Clone ID: Clone: dG9