Anti-Hu CD147 Purified BSG Monoclonal Antibody

Anti-Hu CD147 Purified BSG Monoclonal Antibody

• Background: CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
• Description: Boster Bio Anti-Hu CD147 Purified BSG Monoclonal Antibody (Catalog# M00248). Tested in Flow Cytometry, IP, WB, IHC-P application(s). This antibody reacts with Human.
• Synonyms: Neurothelin, Basigin, LAM6, CSF, 5F7, TCSF, BSG, TCSF, Emprin, OK blood group
• CAS Number: 9007-83-4
• Gene Name: BSG
• UniProt: P35613
• Host: Mouse
• Reactivity: Human
• Immunogen: Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer). The antibody MEM-M6/1 recognizes an extracellular epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
• Clonality: Monoclonal
• Applications: Flow Cytometry, IP, WB, IHC-P
• Purification: Purified by protein-A affinity chromatography.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 42200 MW
• Components: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage Conditions: Store at 2-8°C. Do not freeze.
• Fragment: Mouse IgG1
• Clone ID: Clone: MEM-M6/1