Recombinant Cynomolgus CD3D&CD3E Heterodimer (C-Fc-Flag&C-Fc-6His)

• Background: T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
• Abbreviation: CD3D&CD3E
• Synonyms: CD3 delta & CD3 epsilon; CD3 delta / epsilon; CD3E & CD3D
• UniProt: Q95LI8; Q95LI5
• Accession Number: Q95LI8&Q95LI5
• Expression System: HEK293 Cells
• Tag: C-Fc-Flag & C-Fc-His
• Sequence: Phe22-Ala105&Gln22-Asp117
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Calculated Molecular Weight: 37 & 38.3 kDa
• Observed Molecular Weight: 40 - 60 kDa
• Formulation: Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
  Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
  Please refer to the specific buffer information in the printed manual.
• Species: Cynomolgus macaques