Recombinant Mouse IL-1 Receptor-Like 2/IL-1RL2/IL-1Rrp2/IL-36R (C-Fc)

• Background:

  Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

• Abbreviation:

  IL-1RL2, IL-1Rrp2, IL-36R

• Synonyms:

  Interleukin-1 receptor-like; IL1RL; IL1R-rp; IL-1Rrp; IL1R-rp2; IL-1Rrp2; IL-36 receptor; IL-36R; Interleukin-1 receptor-like 2; Il1rl2

• UniProt:

  Q9ERS7

• Accession Number:

  Q9ERS7

• Expression System:

  HEK293 Cells

• Tag:

  C-Fc

• Sequence:

  Asp22-Arg338 (Ala158Val)

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  63.0 kDa

• Observed Molecular Weight:

  85 - 120 kDa

• Formulation:

  Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
  Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
  Please refer to the specific buffer information in the printed manual.

• Species:

  Mouse