c-Met-IN-24
CAT:
804-HY-162803
Size:
Inquire
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
c-Met-IN-24
- UNSPSC Description: c-Met-IN-24 (compound 3g) is a dual-target inhibitor of STAT-3 ([1]=4.7 μM) and c-MET ([1]=12.67 μM) with anticancer activity. c-Met-IN-24 arrests the G2/M cell cycle and induces apoptosis in SNB-75 cells. c-Met-IN-24 can be used in the study of central nervous system cancers[1].
- Target Antigen: Apoptosis; c-Met/HGFR; STAT
- Type: Reference compound
- Related Pathways: Apoptosis;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/c-met-in-24.html
- Smiles: COC1=CC=CC2=C1OC(C(C3=CSC(NNC(NC4=CC=C(Cl)C=C4)=O)=N3)=C2)=O
- Molecular Weight: 442.88
- References & Citations: [1]Naguib, et al. "Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents." Bioorganic Chemistry (2024): 107682.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported