Mouse Thrombospondin Type-1 Domain-Containing Protein 1, Thsd1 Primacu™ ELISA Kit

• Background:

  Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.

• Description:

  Thrombospondin type-1 domain-containing protein 1

• Synonyms:

  Tmtsp

• Gene Name:

  Thsd1

• Gene ID:

  56229

• UniProt:

  Q9JM61

• Origin Species:

  Mouse

• Reactivity:

  Mouse

• Target:

  THSD1

• Field of Research:

  Cardiovascular,Cell biology,Tags & cell markers

• Assay Type:

  Sandwich

• Assay Performance Time:

  3.5 Hours

• Standard:

  40 ng/mL

• Sample Type:

  Serum, plasma, cell culture supernates

• Detection Range:

  62.5-4000 pg/mL

• Sensitivity:

  16.94 pg/mL

• Weight:

  94696

• Storage Temperature:

  2-8°C