MAO-B-IN-8

• CAS Number:

  1638956-60-1

• UNSPSC Description:

  MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research[1].

• Target Antigen:

  Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mao-b-in-8.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  COC1=C(C(OC)=C(C=C1)/C=C2OC3=C(C\2=O)C=CC(O)=C3)OC

• Molecular Weight:

  328.32

• References & Citations:

  [1]Ahmed H E Hassan, et al. Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases. J Enzyme Inhib Med Chem. 2022 Dec;37(1):768-780.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported