PI3Kα-IN-11

• CAS Number:

  300803-79-6

• UNSPSC Description:

  PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kα-in-11.html

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1NC2=C(C(O)=C1C(NCC3=CC=CC=C3)=O)C=CC=C2

• Molecular Weight:

  294.30

• References & Citations:

  [1]Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα). Bioorg Med Chem. 2012 Dec 15;20(24):7175-83.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported