THP-1/MV-4-11 against-1

• CAS Number:

  2978623-53-7

• UNSPSC Description:

  THP-1/MV-4-11 against-1 (compound 12k) is an anticancer agent with potency inhibitory against THP-1/MV/4 cells (IC50=29 nM and 98 nM, respectively). THP-1/MV-4-11 against-1 is one of 5-substituted thiazolyl urea derivatives, can be used in leukemic diseases research[1].

• Target Antigen:

  Drug Derivative

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/thp-1-mv-4-11-against-1.html

• Smiles:

  O=C(N1CCN(CC1)C2=CC=C(C=C2)Cl)NC3=NC=C(CC4=CC=C(C=C4)OC)S3

• Molecular Weight:

  442.96

• References & Citations:

  [1]Peng C, et al. The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives. Bioorg Med Chem Lett. 2025 Jan 1;115:130018.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported