Enrofloxacin (monohydrochloride)

• CAS Number:

  93106-59-3

• UNSPSC Description:

  Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).

• Target Antigen:

  Antibiotic; Bacterial; Endogenous Metabolite; Orthopoxvirus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/enrofloxacin-monohydrochloride.html

• Purity:

  98.94

• Solubility:

  DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 7.14 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(CC)CC4)=C3)C1=O)O.[H]Cl

• Molecular Weight:

  395.86

• References & Citations:

  [1]Sulyok KM, et al.Antibiotic susceptibility profiles of Mycoplasma bovis strains isolated from cattle in Hungary, Central Europe. BMC Vet Res. 2014 Oct 25;10:256.|[2]Hetze S, et al. Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach. J Cereb Blood Flow Metab. 2013 Jun;33(6):846-54.|[3]S Ikeda , et al. Antiviral activity and inhibition of topoisomerase by ofloxacin, a new quinolone derivative. Antiviral Res. 1987 Oct;8(3):103-13.Aquaculture. 30 January 2022, 737541.|Chemosphere. 2023 Nov, 340, 139892.|Phys Chem Res. 2021 9(2): 327-344.|bioRxiv. 2024 Nov 06.|Cell Rep. 2023 Mar 21;42(4):112290.|Cell Rep. 2024 Feb 17;43(2):113804.|Chemosphere. 2019 Jun;225:378-387. |Curr Biol. 2024 May 21:S0960-9822(24)00603-1.|Neuron. 2021 Aug 18;109(16):2573-2589.e9.|Vet Microbiol. 2024 May, 292, 110046.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported