Active D-2-Hydroxyglutaratate Dehydrogenase (D2HGDH), Recombinant

• Description:

  D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays.

• CAS Number:

  9000-83-3

• Shipping Conditions:

  Gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  12 months