The CMT-93 cell line is a well-established murine colorectal carcinoma model widely used in cancer research, immunology, and drug discovery. Due to its epithelial origin and reproducible growth characteristics, CMT-93 cells are particularly valuable for studying intestinal tumor biology and host–microbiome interactions.

With increasing demand in oncology and inflammation research, understanding how to properly use and source CMT-93 cells is essential for laboratories seeking reliable experimental results.

CMT-93 cells are derived from a mouse rectal carcinoma and exhibit epithelial morphology. These cells are commonly used as an in vitro model for colorectal cancer.

Key Characteristics :

- Species : Mouse (murine).

- Tissue : Rectal carcinoma.

- Morphology : Epithelial-like.

- Growth : Adherent.

- Applications : Cancer biology, inflammation, dr ug screening.

1. Cancer Research

CMT-93 cells are widely used to study :

- Tumor progression.

- Cell proliferation.

- Apoptosis mechanisms.

2. Dr ug Screening

Researchers use this cell line to :

- Evaluate anti-cancer compounds.

- Test chemotherapy responses.

- Study targeted therapies.

3. Microbiome & Inflammation Studies

Due to their intestinal origin :

- Useful for gut-related studies.

- Host-pathogen interaction models.

- Inflammatory signaling pathways.

Proper cell culture is critical for reproducibility.

Recommended Conditions :

- Medium : DMEM (high glucose)

- Supplements : 10% FBS + antibiotics

- Temperature : 37°C

- CO₂ : 5%

- Culture type : Adherent monolayer

Tips :

- Avoid over-confluency.

Passage regularly (70–80% confluence).

- Use sterile techniques to prevent contamination.

Compared to other colorectal cancer models, CMT-93 cells offer :

✔ High reproducibility.

✔ Stable growth characteristics.

✔ Strong relevance for intestinal cancer studies.

✔ Compatibility with murine models.

What are CMT-93 cells used for?

=> They are mainly used in colorectal cancer research, drug screening, and inflammation studies.

Are CMT-93 cells human or mouse?

=> They are derived from mouse (murine) rectal carcinoma.

What medium is used for CMT-93 cells?

=> Typically DMEM supplemented with 10% fetal bovine serum.

Where can I buy CMT-93 cells?

=> From gentaur we offer validated and contamination-free cell lines.