FenicsBIO
FenicsBIO is a U.S.-based biotechnology company specializing in functional genomics tools and services. Headquartered in Halethorpe, Maryland, FenicsBIO offers a comprehensive range of products and services to support gene function studies, drug discovery, and cell-based research.
Core Offerings
1. Lentiviral Gene Editing Tools
- Lentiviral shRNA Gene Knockdown Kits: These kits include pre-designed shRNA constructs and RT-PCR primers, ensuring efficient gene knockdown in mammalian cells. Options include constitutive, inducible, and tissue-specific promoters. The inducible system utilizes doxycycline to control gene expression, providing temporal regulation.
- Lentiviral sgRNA Gene Knockout Kits: Designed for CRISPR/Cas9-mediated gene knockout, these kits provide a set of three sgRNAs targeting each human gene, enhancing knockout efficiency. They also include Indel PCR primers for screening knockout clones.
- Premade Lentivirus: FenicsBIO offers ready-to-use lentiviral particles for various applications, including fluorescent and luciferase reporter systems, Cre recombinase, iPS reprogramming, and signaling pathway reporters.
2. Stable Cell Line Generation
FenicsBIO provides one-stop services for generating stable cell lines, including construct generation, lentivirus production, transduction, and validation assays such as Western blot, FACS, and RT-PCR. They support a wide range of mammalian cell types, including hard-to-transfect and primary cells.
3. Lentivirus Production Services
The company offers custom lentivirus production with options for different envelope proteins (e.g., VSV-G, MuLV, Rabies, SARS-CoV-2 spike). Services include functional titration, serum-free preparation suitable for both in vitro and in vivo applications, and storage in LentiShield™ buffer to maintain viral titer after freeze-thaw cycles.
4. Custom Cloning Services
FenicsBIO's custom cloning services encompass cDNA, shRNA, and CRISPR-Cas9 construct generation. They offer a large collection of lentiviral cloning vectors and provide assistance with vector design, sequence verification, and plasmid preparation.
Research Areas
FenicsBIO supports various research domains, including:
- Gene Editing: Tools for CRISPR/Cas9-mediated gene knockout and knockdown.
- Inducible Gene Expression: Tet-inducible systems for controlled gene expression.
- iPSC Generation: Reprogramming somatic cells into induced pluripotent stem cells.
- In Vivo Imaging: Luciferase and fluorescent reporter systems for live-cell imaging.
- Signal Transduction: Pathway reporter systems to study cellular signaling.
- COVID-19 Research: Lentiviral ORF plasmids, sgRNA kits, and stable cell lines for SARS-CoV-2 studies
22Rv1 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423066|Size: 1 Vial
22Rv1/GFP stable cell line
SKU: GTR15423289|Size: 1 Vial
22Rv1/Luciferase stable cell line
SKU: GTR15424136|Size: 1 Vial
22Rv1/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423940|Size: 1 Vial
22Rv1/RFP stable cell line
SKU: GTR15423054|Size: 1 Vial
22Rv1/RFP-luciferase stable cell line
SKU: GTR15423304|Size: 1 Vial
22Rv1/STAT3 Reporter (Luc) stable cell line
SKU: GTR15424049|Size: 1 Vial
22Rv1/STAT5 Reporter (GFP) stable cell line
SKU: GTR15424144|Size: 1 Vial
22Rv1/STAT5 Reporter (Luc) stable cell line
SKU: GTR15424004|Size: 1 Vial
22Rv1/iRFP stable cell line
SKU: GTR15424033|Size: 1 Vial
4T1 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423097|Size: 1 Vial
4T1/GFP stable cell line
SKU: GTR15424086|Size: 1 Vial
4T1/Luciferase stable cell line
SKU: GTR15423930|Size: 1 Vial
4T1/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423621|Size: 1 Vial
4T1/RFP stable cell line
SKU: GTR15423879|Size: 1 Vial
4T1/RFP-luciferase stable cell line
SKU: GTR15423103|Size: 1 Vial
4T1/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423361|Size: 1 Vial
4T1/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423398|Size: 1 Vial
4T1/STAT5 Reporter (Luc) stable cell line
SKU: GTR15424135|Size: 1 Vial
4T1/iRFP stable cell line
SKU: GTR15423538|Size: 1 Vial
5637 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423600|Size: 1 Vial
5637/GFP stable cell line
SKU: GTR15423328|Size: 1 Vial
5637/Luciferase stable cell line
SKU: GTR15424245|Size: 1 Vial
5637/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423552|Size: 1 Vial
5637/RFP stable cell line
SKU: GTR15424001|Size: 1 Vial
5637/RFP-luciferase stable cell line
SKU: GTR15423677|Size: 1 Vial
5637/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423258|Size: 1 Vial
5637/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423639|Size: 1 Vial
5637/STAT5 Reporter (Luc) stable cell line
SKU: GTR15424151|Size: 1 Vial
5637/iRFP stable cell line
SKU: GTR15423364|Size: 1 Vial
786-O SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15424123|Size: 1 Vial
786-O/GFP stable cell line
SKU: GTR15423979|Size: 1 Vial
786-O/Luciferase stable cell line
SKU: GTR15423956|Size: 1 Vial
786-O/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423658|Size: 1 Vial
786-O/RFP stable cell line
SKU: GTR15423819|Size: 1 Vial
786-O/RFP-luciferase stable cell line
SKU: GTR15423766|Size: 1 Vial
786-O/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423701|Size: 1 Vial
786-O/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423494|Size: 1 Vial
786-O/STAT5 Reporter (Luc) stable cell line
SKU: GTR15423301|Size: 1 Vial
786-O/iRFP stable cell line
SKU: GTR15424133|Size: 1 Vial
A-253 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423127|Size: 1 Vial
A-253/GFP stable cell line
SKU: GTR15423804|Size: 1 Vial
A-253/Luciferase stable cell line
SKU: GTR15423588|Size: 1 Vial
A-253/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423087|Size: 1 Vial
A-253/RFP stable cell line
SKU: GTR15423618|Size: 1 Vial
A-253/RFP-luciferase stable cell line
SKU: GTR15424074|Size: 1 Vial
A-253/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423198|Size: 1 Vial
A-253/STAT5 Reporter (GFP) stable cell line
SKU: GTR15424020|Size: 1 Vial
A-253/STAT5 Reporter (Luc) stable cell line
SKU: GTR15424066|Size: 1 Vial
A-253/iRFP stable cell line
SKU: GTR15423105|Size: 1 Vial
A20 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423083|Size: 1 Vial
A20/GFP stable cell line
SKU: GTR15423712|Size: 1 Vial
A20/Luciferase stable cell line
SKU: GTR15423995|Size: 1 Vial
A20/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423422|Size: 1 Vial
A20/RFP stable cell line
SKU: GTR15423410|Size: 1 Vial
A20/RFP-Luciferase stable cell line
SKU: GTR15423121|Size: 1 Vial
A20/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423598|Size: 1 Vial
A20/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423551|Size: 1 Vial
A20/STAT5 Reporter (Luc) stable cell line
SKU: GTR15423267|Size: 1 Vial
A20/iRFP stable cell line
SKU: GTR15424047|Size: 1 Vial
A375 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15424252|Size: 1 Vial
A375/GFP stable cell line
SKU: GTR15423226|Size: 1 Vial
A375/Luciferase stable cell line
SKU: GTR15423687|Size: 1 Vial
A375/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423573|Size: 1 Vial
A375/RFP stable cell line
SKU: GTR15423810|Size: 1 Vial
A375/RFP-luciferase stable cell line
SKU: GTR15423601|Size: 1 Vial
A375/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423867|Size: 1 Vial
A375/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423452|Size: 1 Vial
A375/STAT5 Reporter (Luc) stable cell line
SKU: GTR15423922|Size: 1 Vial
A375/iRFP stable cell line
SKU: GTR15423269|Size: 1 Vial
A549 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423427|Size: 1 Vial
A549/GFP stable cell line
SKU: GTR15423145|Size: 1 Vial
A549/IFN beta reporter (GFP) cell line
SKU: GTR15423781|Size: 1 Vial
A549/Luciferase stable cell line
SKU: GTR15423262|Size: 1 Vial
A549/NF-kB Reporter (Luc) stable cell line
SKU: GTR15424003|Size: 1 Vial
A549/RFP stable cell line
SKU: GTR15424090|Size: 1 Vial
A549/RFP-luciferase stable cell line
SKU: GTR15423952|Size: 1 Vial
A549/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423412|Size: 1 Vial
A549/STAT5 Reporter (GFP) stable cell line
SKU: GTR15423918|Size: 1 Vial
A549/STAT5 Reporter (Luc) stable cell line
SKU: GTR15424080|Size: 1 Vial
A549/iRFP stable cell line
SKU: GTR15423610|Size: 1 Vial
ACE2 lentivirus (CMV, Puro) - ACE2 lentivirus (CMV, Puro)
SKU: GTR15424787|Size: 25 µL (1x 25 µL)
ASCL1 lentivirus (TET-inducible, Puro) - ASCL1 lentivirus (TET-inducible, Puro)
SKU: GTR15424599|Size: 25 µL (1x 25 µL)
ATDC5 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423567|Size: 1 Vial
ATDC5/GFP stable cell line
SKU: GTR15423945|Size: 1 Vial
ATDC5/Luciferase stable cell line
SKU: GTR15423281|Size: 1 Vial
ATDC5/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423719|Size: 1 Vial
ATDC5/RFP stable cell line
SKU: GTR15423630|Size: 1 Vial
ATDC5/RFP-Luciferase stable cell line
SKU: GTR15424142|Size: 1 Vial
ATDC5/STAT3 Reporter (Luc) stable cell line
SKU: GTR15423068|Size: 1 Vial
ATDC5/iRFP stable cell line
SKU: GTR15424170|Size: 1 Vial
Ars2 lentivirus (TET-inducible, Puro) - Ars2 lentivirus (TET-inducible, Puro)
SKU: GTR15424771|Size: 25 µL (1x 25 µL)
AsPC-1 SMAD/TGFbeta Reporter (Luc) stable cell line
SKU: GTR15423424|Size: 1 Vial
AsPC-1/GFP stable cell line
SKU: GTR15424103|Size: 1 Vial
AsPC-1/GFP-luciferase stable cell line
SKU: GTR15423199|Size: 1 Vial
AsPC-1/Luciferase stable cell line
SKU: GTR15423275|Size: 1 Vial
AsPC-1/NF-kB Reporter (Luc) stable cell line
SKU: GTR15423116|Size: 1 Vial
AsPC-1/RFP stable cell line
SKU: GTR15423118|Size: 1 Vial
AsPC-1/RFP-Luciferase stable cell line
SKU: GTR15423882|Size: 1 Vial
AsPC-1/STAT3 Reporter (Luc) stable cell line
SKU: GTR15424197|Size: 1 Vial